Pipeline

Cantabio's core research strategy focuses on the development of a pipeline of therapeutic candidates with novel mechanisms of action for preclinical testing and clinical development for Alzheimer’s and Parkinson’s diseases and related indications. Cantabio’s pipeline represents a balanced R&D strategy aimed at generating a return on research and development investment, with a throughput of therapeutic candidates at different R&D stages ensuring a continuous supply of clinical candidates.

Cantabio is constantly searching for complementary technologies and R&D partnerships to complement the companies’ core scientific and technological intellectual property and capabilities. Cantabio has an on-going policy of review and acquisition of complementary intellectual property, whilst also pursing out-licensing opportunities of its selected therapeutic projects.

Product & Indication Development Stage
Preclinical Phase 1 Phase 2 Phase 3
CB101

Parkinson's Disease

DJ-1 targeting small molecule pharmacological chaperone

Upcoming Milestones:
  • Selection of clinical candidate in 2018
  • Expect to file IND in 2019

Commercial Rights: Cantabio

Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
CB201

Alzheimer's and Parkinson's Disease

Cell penetrant DJ-1 protein

Upcoming Milestones:
  • Expect to file IND in 2017

Commercial Rights: Cantabio

Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
CB301

Alzheimer's Disease

Tau targeting small molecule pharmacological chaperone

Licensed from University of Cambridge - cellular and in vivo data, ongoing in vivo studies

Commercial Rights: Cantabio

Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
CB401

Alzheimer's Disease

Aβ targeting small molecule pharmacological chaperone

Currently in proof of concept studies

Commercial Rights: Cantabio

Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started